FB2025_01 , released February 20, 2025
Gene Group: ASPARTIC PEPTIDASES
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General Information
Name
ASPARTIC PEPTIDASES
Species
D. melanogaster
Symbol
APEPT
FlyBase ID
FBgg0001398
Date last reviewed
2020-06-08
Number of members
17
Description
Description
Aspartic peptidases catalyse the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
Notes on Group
Source Material
The ASPARTIC PEPTIDASES Gene Group has been compiled using the following publication(s): Casso et al., 2012, Morawe et al., 2011, Narayanan et al., 2007, Ponting et al., 2002, and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
aspartic-type peptidase activity
Biological Process
proteolysis
Cellular Component
Related Gene Groups
Parent group(s)
PEPTIDASES
Component group(s)
A1 ASPARTIC ENDOPEPTIDASES
A22 ASPARTIC ENDOPEPTIDASES
A28 ASPARTIC ENDOPEPTIDASES
Members (17)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
A1 ASPARTIC ENDOPEPTIDASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Bace
beta-site APP-cleaving enzyme
dBACE
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
cathD
cathepsin D
CTSD
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG5860
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG5863
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG6508
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG10104
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG17134
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG17283
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG31661
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG31926
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG31928
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
CG33128
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
Pgcl
Pepsinogen C-like
T2, pcl, EG:EG0001.1, pepsinogen-like, scβ
(FlyBase, 2017-, Rawlings and Barrett, 1996-)
A22 ASPARTIC ENDOPEPTIDASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Psn
Presenilin
PS, γ-secretase, dPsn, Dps, dPresenilin
(FlyBase, 2017-, Ponting et al., 2002, Rawlings and Barrett, 1996-)
Spp
Signal peptide peptidase
shanti, Signal peptide protease
(FlyBase, 2017-, Casso et al., 2012, Narayanan et al., 2007, Ponting et al., 2002, Rawlings and Barrett, 1996-)
SppL
Signal peptide peptidase-like
(FlyBase, 2017-, Casso et al., 2012, Narayanan et al., 2007, Ponting et al., 2002, Rawlings and Barrett, 1996-)
A28 ASPARTIC ENDOPEPTIDASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
rngo
rings lost
(FlyBase, 2017-, Morawe et al., 2011, Rawlings and Barrett, 1996-)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
APEPT
ASPARTIC PEPTIDASES
Aspartic-type peptidases
Secondary FlyBase ID(s)
References (7)