FB2025_01 , released February 20, 2025
Gene Group: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS
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General Information
Name
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS
Species
D. melanogaster
Symbol
MC-AF
FlyBase ID
FBgg0002035
Date last reviewed
2024-11-07
Number of members
61
Description
Description
The assembly of the mitochondrial respiratory chain complexes (complexes I-IV) is a highly coordinated multistep process that employs assembly factors which transiently associate with complex subunits, sub-complexes and cofactors to assemble the functional holoenzymes. (Adapted from PMID:38086790).
Notes on Group
Source Material
The MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS Gene Group has been compiled using the following publication(s): Attrill, 2024.11.14, Murari et al., 2021, and So et al., 2021 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mitochondrial respiratory chain complex assembly
Cellular Component
mitochondrial inner membrane
Related Gene Groups
Parent group(s)
MITOCHONDRIAL OXPHOS COMPLEX ASSEMBLY FACTORS
Component group(s)
MITOCHONDRIAL RESPIRASOME ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX II ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX III ASSEMBLY FACTORS
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX IV ASSEMBLY FACTORS
Members (61)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
MITOCHONDRIAL RESPIRASOME ASSEMBLY FACTORS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG9921
(Attrill, 2024.11.14)
CG11825
(Attrill, 2024.11.14)
CG12107
(Attrill, 2024.11.14)
CG17734
(Attrill, 2024.11.14)
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY FACTORS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG3270
(Attrill, 2024.11.14)
CG8067
(Attrill, 2024.11.14)
CG15653
(Attrill, 2024.11.14)
CG17726
(Attrill, 2024.11.14)
CG31913
(Attrill, 2024.11.14)
CG34229
(Attrill, 2024.11.14)
CG42380
(Attrill, 2024.11.14)
CG43346
(Attrill, 2024.11.14)
Dmac2
Distal membrane arm assembly component 2
(Attrill, 2024.11.14, Murari et al., 2021)
ECSIT
ECSIT
dECSIT
(Attrill, 2024.11.14, Murari et al., 2021)
Egm
Enigma
l(2)k14708
(Attrill, 2024.11.14, Murari et al., 2021)
l(2)37Bb
lethal (2) 37Bb
l(2)E58, Bb
(Attrill, 2024.11.14, Murari et al., 2021)
NdufAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1
CIA30, dNDUFAF1, dCIA30
(Attrill, 2024.11.14, Murari et al., 2021)
NdufAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
dNDUFAF3
(Attrill, 2024.11.14, Murari et al., 2021)
NdufAF4
NADH:ubiquinone oxidoreductase complex assembly factor 4
dNDUFAF4
(Attrill, 2024.11.14, Murari et al., 2021)
Nubpl
NUBP iron-sulfur cluster assembly factor, mitochondrial
(Attrill, 2024.11.14, So et al., 2021)
sicily
severe impairment of CI with lengthened youth
dNDUFAF6
(Attrill, 2024.11.14, Murari et al., 2021)
Timmdc1
Translocase of inner mitochondrial membrane domain containing 1
140up, DmRP140-upstream, l(3)Z6
(Attrill, 2024.11.14, Murari et al., 2021)
Tmem70
Transmembrane protein 70
(Murari et al., 2021)
Tmem126
Transmembrane protein 126
(Attrill, 2024.11.14, Murari et al., 2021)
Tmem186
Transmembrane protein 186
(Attrill, 2024.11.14, Murari et al., 2021)
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX II ASSEMBLY FACTORS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG12895
(Attrill, 2024.11.14)
CG14757
(Attrill, 2024.11.14)
CG15283
BG:DS08340.1
(Attrill, 2024.11.14)
Sdhaf3
Succinate dehydrogenase assembly factor 3
(Attrill, 2024.11.14)
Sirup
Starvation-upregulated protein
dSdhaf4, Sdhaf4
(Attrill, 2024.11.14)
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX III ASSEMBLY FACTORS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Bcs1
Bcs1 chaperone
(Attrill, 2024.11.14)
CG15386
(Attrill, 2024.11.14)
CG30373
(Attrill, 2024.11.14)
CG34150
(Attrill, 2024.11.14)
CG46459
(Attrill, 2024.11.14)
sloth1
sloth 1
(Attrill, 2024.11.14)
sloth2
sloth 2
(Attrill, 2024.11.14)
Ttc19
Tetratricopeptide repeat domain 19
(Attrill, 2024.11.14)
Uqcc1
Ubiquinol-cytochrome c reductase complex assembly factor 1
(Attrill, 2024.11.14)
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX IV ASSEMBLY FACTORS
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Ccdc56
Coiled-coil domain containing 56
(Attrill, 2024.11.14)
Cep89
Centrosomal protein 89kDa
(Attrill, 2024.11.14)
CG4186
(Attrill, 2024.11.14)
CG4942
(Attrill, 2024.11.14)
CG11562
(Attrill, 2024.11.14)
CG12935
(Attrill, 2024.11.14)
CG13018
(Attrill, 2024.11.14)
CG14483
(Attrill, 2024.11.14)
CG15653
(Attrill, 2024.11.14)
CG17776
(Attrill, 2024.11.14)
CG17996
(Attrill, 2024.11.14)
CG31913
(Attrill, 2024.11.14)
CG34242
(Attrill, 2024.11.14)
CG42375
(Attrill, 2024.11.14)
CG42376
(Attrill, 2024.11.14)
CG42496
(Attrill, 2024.11.14)
CG44194
(Attrill, 2024.11.14)
Coa7
Cytochrome c oxidase assembly factor 7
dCOA7
(Attrill, 2024.11.14)
Cox11
Cytochrome c oxidase copper chaperone COX11
(Attrill, 2024.11.14)
Cox17
Cytochrome c oxidase copper chaperone COX17
(Attrill, 2024.11.14)
l(3)87Df
lethal (3) 87Df
l(3)S12, S12
(Attrill, 2024.11.14)
l(3)neo43
lethal (3) neo43
(Attrill, 2024.11.14)
Scox
Synthesis of cytochrome c oxidase
(Attrill, 2024.11.14)
Surf1
Surfeit 1
Surfeit locus protein 1, SUR1
(Attrill, 2024.11.14)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
MC-AF
MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS
Secondary FlyBase ID(s)
References (4)