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Reference Report
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| Citation | Marsano, R.M., Moschetti, R., Caggese, C., Lanave, C., Barsanti, P., Caizzi, R. (2000). The complete Tirant transposable element in Drososphila melanogaster shows a structural relationship with retrovirus-like retrotransposons. Gene 247(1-2): 87--95. (Export to RIS) | ||
| FlyBase ID | FBrf0127224 | ||
| Publication Type | Research paper | ||
| PubMed ID | 10773447 | ||
| PubMed Abstract | We have determined the structure and organization of Tirant, a retrotransposon of Drosophila melanogaster reported in literature to be responsible for four independent mutations. Tirant is a long terminal repeat (LTR) retrotransposon 8527bp long. It possesses three open reading frames (ORF) encoding Gag, Pol and Env proteins with a strong similarity with ZAM, a recently identified member of the gypsy class of retrovirus-like mobile elements. Molecular analysis of the Tirant genomic copies present in four D. melanogaster strains revealed that most of them are defective, non-autonomous elements that differ in the position and extension of the conserved internal portion. Defective elements lacking the Gag ORF but retaining the Env ORF are abundant in heterochromatin. Four discrete Tirant transcripts are observed during embryogenesis in the strain Oregon-R, the smaller of which, 1.8kb in size, originates from the splicing of a primary transcript and leads to a subgenomic RNA coding for the Env product. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Gene | ||
| Title | Gene | ||
| Publication Year | 1976- | ||
| ISBN/ISSN | 0378-1119 | ||
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Data from Reference
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| Genes (3)
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| Natural transposons (9)
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