FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of complement activation ID (Ontology) GO:0045916 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.
Also Known As "down regulation of complement activation" ; "down-regulation of complement activation" ; "downregulation of complement activation" (for all, see Synonyms field below)
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negative regulation of immune system process
 |__negative regulation of immune effector process__
regulation of immune effector process               |
 |__negative regulation of immune effector process__|
 |__regulation of complement activation_____________|
regulation of humoral immune response               |
 |__negative regulation of humoral immune response__|
 |__regulation of complement activation_____________|
complement activation                               |
 |__regulation of complement activation_____________|
negative regulation of immune response              |
 |__negative regulation of humoral immune response__|
                                                    negative regulation of complement activation
                                                     |__negative regulation of activation of membrane attack complex
                                                     |__negative regulation of complement activation, alternative pathway
                                                     |__negative regulation of complement activation, classical pathway
                                                     |__negative regulation of complement activation, lectin pathway
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Is a negative regulation of immune effector process
negative regulation of humoral immune response
regulation of complement activation
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Synonyms
  • "down regulation of complement activation" EXACT
    "down-regulation of complement activation" EXACT
    "downregulation of complement activation" EXACT
    "inhibition of complement activation" NARROW
    "negative regulation of complement cascade" EXACT
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