FB2026_03 , released September 17, 2026
Aberration: Dmel\Dp(2;2)Su(Pm)
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General Information
Symbol
Dp(2;2)Su(Pm)
Species
D. melanogaster
Name
Duplication (2;2) Suppressor of Plum
FlyBase ID
FBab0003506
Feature type
tandem_duplication
Computed Cytological Breakpoints (relative to progenitor)

59D4--E1;[>59E2]

Features within 59D4--59E2
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
(Kadel, 1959)
Class of aberration (relative to wild type)
tandem_duplication
(FlyBase, 2007)
Class of aberration (relative to progenitor)
tandem_duplication
Cytological Breakpoints (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << bw << bk2

Genetic mapping information
Comments
Comments on Cytology

Tandem duplication of the bw gene and flanking sequences with 59E.

(Henikoff et al., 1995)

Tandem duplication of the bw region.

(Henikoff and Dreesen, 1989)

Left limit of break 1 from polytene analysis (citation unavailable) Right limit of break 1 from inclusion of bw (FBrf0050859) Left limit of break 2 from inclusion of bw (FBrf0050859)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
bw
(Henikoff and Dreesen, 1989)
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Associated with a semilethal mutation or is tightly linked to one. Homozygous male escapers are healthy and fertile.

    (Henikoff et al., 1995)

    Homozygous lethal.

    (Kadel, 1959)

    Dp(2;2)Su(Pm)/bwV1 has wild-type eye color with peppering of dark spots instead of the more or less uniform brown of bwV1/+. Effect on various bwV chromosomes varies from none for some to complete suppression for others. Pteridines of heads of bwD/bw Dp(2;2)Su(Pm) heterozygotes increased to 28% of normal from 2.5% for bwD/+ heterozygotes (Henikoff and Dreesen). Homozygous viable.

    Stocks (0)
    Notes on Origin
    Discoverer

    Kadel, 17th Feb. 1959.

     
    Balancer / Genotype Variants of the Aberration
    Separable Components
     
    Other Comments
     

    Suppression of variegation by Dp(2;2)Su(Pm) is caused by the tandem duplication itself as the suppression disappears when the active copy of bw is separated from the duplication.

    (Henikoff and Dreesen, 1989)
    Synonyms and Secondary IDs (11)
    Reported As
    Symbol Synonym
    Dp(2;2)59E
    (Henikoff et al., 1995)
    Dp(2;2)Byron
    (Weiler and Chatterjee, 2009)
    Dp(2;2)Su(Pm)
    Su(Pm)
    Su(bwV1)
    Su(bwV1)1
    Su-Pm
    (Kadel, 1959)
    Name Synonyms
    Duplication (2;2) Suppressor of Plum
    Suppressor of Plum
    (Kadel, 1959)
    Suppressor of brown-Variegated
    Suppressor-of-Plum
    Secondary FlyBase IDs
    • FBgn0010089
    • FBal0016253
    References (7)