FB2026_03 , released September 17, 2026
Aberration: Dmel\In(1)Mud
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General Information
Symbol
In(1)Mud
Species
D. melanogaster
Name
Inversion (1) Muddled
FlyBase ID
FBab0003992
Feature type
chromosomal_inversion
Computed Cytological Breakpoints (relative to progenitor)

3C3-3C4;5A6-5B1

Features within 3C--5A (Estimated cytology)
Genomic Maps
Sequenced Breakpoints (relative to progenitor)
X:2,993,834..2,993,834 (In(1)Mud:bk1)
(Islam et al., 2021)
X:5,592,255..5,592,255 (In(1)Mud:bk2)
(Islam et al., 2021)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
Cytological Breakpoints (relative to progenitor)
Causes alleles
Mudd1
(Islam et al., 2021, Lindsley and Zimm, 1992)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << Mud << bk2

Genetic mapping information
Comments

The 3C inversion breakpoint is located 20kb upstream of rst. The 5A breakpoint maps to the intergenic region between Vsx1 and Vsx2, 2.7kb upstream of Vsx1. Expression of Vsx1 in the center of the outer proliferation center is completely lost in the inversion chromosome (presumably due to the inversion of Vsx1 cis-regulatory sequences distal to the 5A breakpoint) and in addition, the inversion places the rst eye enhancer upstream of Vsx1, resulting in ectopic expression of Vsx1 posterior to the morphogenetic furrow in the eye disc.

(Islam et al., 2021)

The In(1)Mud breakpoints were roughly mapped and reported to extend from 20kb upstream of rst to 2kb upstream of Vsx1.

(Islam et al., 2021)
Comments on Cytology

All limits from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Vsx1
(Islam et al., 2021)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations
    Stocks (1)
    Notes on Origin
    Discoverer

    Grell.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    In(1)Mud
    Name Synonyms
    Inversion (1) Muddled
    Secondary FlyBase IDs
      References (4)