FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Ab(3L;h)ME178
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General Information
Symbol
Ab(3L;h)ME178
Species
D. melanogaster
Name
FlyBase ID
FBab0023374
Feature type
chromosome_structure_variation
Computed Breakpoints include

78A7-78B1

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Russell et al., 1996, Carpenter, 1994)
Class of aberration (relative to wild type)
chromosome_structure_variation
Class of aberration (relative to progenitor)
Breakpoints

78A7-78B1;het

(Russell et al., 1996, Carpenter, 1994)
Causes alleles
l(3)78Ad1
(Carpenter, 1998.11.24)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology

Maybe an inversion or translocation.

(Russell et al., 1996)

May be a translocation or an inversion.

(Carpenter, 1994)

All limits from polytene analysis (FBrf0075380)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
l(3)78Ad
(Carpenter, 1998.11.24)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    Fails to complement 78C deficiencies (no visible cytological defect) and fails to complement 78A deficiencies.

    (Russell et al., 1996)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer

    A.T.C. Carpenter.

    (Carpenter, 1994)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Lethal in 78A and 78C, although there is no visible cytological defect there even in asynapsed chromosomes. Mapping of the lethal is complicated by the facts that when Ab(3L;h)ME178 is transmitted by the mother it is viable over most other 78C lethals and deficiencies, and even when it is transmitted by the father it leaks. It is nearly lethal over most Pc deficiencies, including In(3)Pc-T7 and Pc3 and Ubx duplication, but is less lethal over Df(3L)Pc-30A is viable over Pc73 and Df(3L)ME1325. Lethal over In(3)80c even when transmitted from female. Completely lethal over Df(3L)ME107 from 78A lesion so 78C lesion cannot be tested. Not phenotypically Pc.

    (Carpenter, 1994)
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Ab(3L;h)ME178
    Ab(3L;h?)ME178
    Df(3L)ME178
    (Onel et al., 2004)
    Name Synonyms
    Secondary FlyBase IDs
      References (4)