FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Abnormal-abdomen53g
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General Information
Symbol
Dmel\Abnormal-abdomen53g
Species
D. melanogaster
Name
FlyBase ID
FBal0000039
Feature type
allele
Associated gene
Abnormal-abdomen
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Epidermal foldings of abdomen abnormal. Tergite formation incomplete, ranging from loss of tergites 2-8 in extreme cases to loss of lateral part of tergite in one or more segments. RK2 in young cultures.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Abnormal-abdomen53g has phenotype, enhanceable by E(A53g)1

      (Thalmann, 1974)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      May not be allelic to A1.

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Hillman, July 1953.

      Comments
      Comments

      Supernatents from homogenates of A53g-bearing adults stimulate amino acid incorporation and aminoacylation of tRNA more than those from wild type (FBrf0020251). Mutant late pupae and adults show increased concentrations of soluble protein. Expression in A53g/A53g females > A53g/Y males > A53g/+ females. Expression maternally influenced (FBrf0026596). Highly variable; sensitive to modifiers on X, 2 and 3, including E(A53g) on 2L. Sensitive to culture conditions; expression reduced in old cultures and under conditions of crowding, low temperature (TSP in late second and early third instar) and low humidity. Also reduced by agents that inhibit RNA or protein synthesis or oxidative phosphorylation (FBrf0025022). Expression of biochemical phenotype correlated with that of visible phenotype (FBrf0025023).

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      A53g
      A53g
      Abnormal-abdomen53g
      Name Synonyms
      Secondary FlyBase IDs
        References (5)