FB2026_02 , released June 18, 2026
Allele: Dmel\abd-AHab-2
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General Information
Symbol
Dmel\abd-AHab-2
Species
D. melanogaster
Name
FlyBase ID
FBal0000088
Feature type
allele
Associated gene
Dmel\abd-A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Shimell et al., 1994)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

Mutation is located within the 1.7kb initiator fragment in the first intron of abd-A, within the Kr binding site. This is the same substitution as in abd-AHab-2 though additional polymorphisms establish that the mutations were independent events.

(Shimell et al., 1994)

Nucleotide substitution: G251A.

(Shimell et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transformation of portions of T3 towards A2, haltere and/or third leg become wing material. More individuals display the transformation at higher temperatures.

      (Shimell et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Duncan.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hab2
      (Shimell et al., 1994)
      abd-AHab-2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)