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General Information
Symbol
Dmel\Abd-BSab-1
Species
D. melanogaster
Name
FlyBase ID
FBal0000147
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

G16878898A

Comment:

A point mutation in a bioinformatically predicted KRUPPEL TFBS in the IAB5 enhancer.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology

Polytene chromosomes normal.

Nature of the lesion
Statement
Reference

Single point mutation (G to A, base position 104543 in GenBank accession U31961) in the centre of the IAB5 cis-regulatory module. This mutation is at the fourth position of the highest scoring predicted Kr protein binding site in the IAB5 enhancer, and is predicted to significantly lower the affinity of Kr protein binding.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

adult cuticle & abdominal segment 3 | male

adult cuticle & abdominal segment 4 | male

Detailed Description
Statement
Reference

In mutant males, abdominal segment A3 (but not A4) shows additional dark pigmentation, suggesting a transformation towards an A5-like identity.

In males homozygous for Abd-BMcp-1,Abd-BSab-1, male specific pigmentation is expanded into A3 and A4.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Sakonju.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Abd-BSab-1
Uab4
Uab4SS
Name Synonyms
Secondary FlyBase IDs
    References (3)