FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\amd40
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General Information
Symbol
Dmel\amd40
Species
D. melanogaster
Name
FlyBase ID
FBal0000489
Feature type
allele
Associated gene
Dmel\amd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Konrad et al., 1993)
Mutagen
ethyl methanesulfonate
(Wright et al., 1982)
gamma ray
(Wright et al., 1982)
Progenitor genotype
Cytology
Description

Elimination of an internal BglII site.

(Stathakis et al., 1995)

Mutation of the intron splice acceptor site at coordinate -4.8, relative to the HpaI restriction site near the 3' end of Ddc.

(Black et al., 1987)

BglII site at -4.8-kb altered; at intron splice acceptor

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
2L:19,112,792..19,112,797 [+]
Comment:

Unspecified change at BglII restriction site in mutant. The BglII site is at a splice acceptor site.

(Black et al., 1987)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Germline clones fail to produce viable eggs. Follicle cell clones also rarely support egg production.

      (Konrad et al., 1993)

      Lethality is at the egg/larval boundary effective lethal phase. Cuticle incompletely sclerotinized and fragile.

      (Wright et al., 1982)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      amd40 is rescued by amd+t2.9

      (Wang and Marsh, 1995)
      Comments

      Mutant phenotype can be rescued by two copies of amd+t2.9.

      (Wang and Marsh, 1995)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wright.

      Selected as: Recessive lethal.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      amd40
      l(2)7439
      l(2)amd40
      (Konrad et al., 1993)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)