FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AntpHu
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General Information
Symbol
Dmel\AntpHu
Species
D. melanogaster
Name
Humeral
FlyBase ID
FBal0000583
Feature type
allele
Associated gene
Dmel\Antp
Associated Insertion(s)
Carried in Construct
Also Known As
Hu
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Scott et al., 1983)
Progenitor genotype
Caused by aberration
In(3R)Hu
Cytology
Description

Based on the breakpoints of In(3R)Hu, the mutation in AntpHu appears to be a regulatory mutation caused by the 84B inversion breakpoint that lies approximately 50kb away from the Antp transcription unit. The 5' end of this breakpoint corresponds to 3R:7048580 and the 3' end corresponds to 3R:7048586 (release 6 coordinates), meaning that 5bp of genomic sequence are deleted, in addition to the inversion.

(Miller et al., 2016)

Proximal inversion breakpoint is at map position +255.

(Scott et al., 1983)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Extra humeral bristles are formed. Does not interact with ph-d1 or ph-d2.

      (Dura et al., 1985)

      Transformation of sternopleural bristles on the propleura to mesopleural identity.

      (Lewis et al., 1980)

      Extra bristles on humerus. Homozygous viable.

      (Lewis et al., 1980)

      Extra humeral bristles.

      (Duncan and Kaufman, 1975)

      Extra bristles on humeral patches of heterozygote. Humeral bristles more numerous in homozygote with a streak of hairs below humerus toward base of first leg. Homozygous viability 90% wild type. RK2A as heterozygote.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer

      Ruch, 1931.

      Comments
      Comments

      Moderate allele.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      AntpHu
      (Miller et al., 2016)
      Hu
      (Dura et al., 1985, Hazelrigg and Kaufman, 1983)
      Hu1
      Name Synonyms
      AntennapaediaHu
      (Grau et al., 2008)
      Humeral
      Secondary FlyBase IDs
        References (17)