FB2026_03 , released September 17, 2026
Allele: Dmel\aperA1
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General Information
Symbol
Dmel\aperA1
Species
D. melanogaster
Name
FlyBase ID
FBal0000665
Feature type
allele
Associated gene
aperA
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Fails to show sugar-induced proboscis extension reflex. Does not cause the degeneration of the rostral protractors. Suppresses muscle degeneration of aperC1.

      (Kimura et al., 1987)

      Fails to show sugar-induced proboscis extension reflex; 47.0% of flies unable to extend their probosces, 16% only to the left side and the remainder extended their probosces normally.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      aperA1 is a suppressor of phenotype of aperC1

      (Kimura et al., 1987)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      aperC1 aperA1 double mutants genetically cannot extend the proboscis and show suppression of aperC1 muscle degeneration.

      (Kimura et al., 1987)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Penetrance about 79%.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TT1
      aperA1
      aperATT1
      (Kimura et al., 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)