FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Brdrv3
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General Information
Symbol
Dmel\Brdrv3
Species
D. melanogaster
Name
FlyBase ID
FBal0001278
Feature type
allele
Associated gene
Dmel\Brd
Associated Insertion(s)
Carried in Construct
Also Known As
Brd1rv3
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Leviten and Posakony, 1996)
Progenitor genotype
Brd1
(Leviten and Posakony, 1996)
Cytology
Description

Nucleotide substitution: T?C. Amino acid replacement: I11T. Nucleotide substitution: C?G and G?A. Amino acid replacement: Q19E.

(Leviten et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:14,972,770..14,972,770 [+]
Nucleotide change:

T14972770C

Reported nucleotide change:

T?C

Amino acid change:

I11T | Brd-PA

Reported amino acid change:

I11T

Comment:

Mutation induced on Brd1 chromosome; one of three base pair changes in mutan, two of which occur in the same codon.

(Leviten et al., 1997)
point_mutation
3L:14,972,793..14,972,793 [+]
Nucleotide change:

C14972793G

Reported nucleotide change:

C?G

Amino acid change:

Q19E | Brd-PA

Reported amino acid change:

Q19E

Comment:

Mutation induced on Brd1 chromosome; one of three base pair changes in mutant, two of which occur in codon Q19 (CAG to GAA).

(Leviten et al., 1997)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Viable when heterozygous with Df(3L)Brd12, adults exhibit no external mutant phenotype.

      (Leviten and Posakony, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Leviten.

      Revertant.

      (Leviten et al., 1997, Leviten and Posakony, 1996)
      Comments
      Comments

      Brd bristle multiplication phenotype is reverted.

      (Leviten and Posakony, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Brd1rv3
      (Leviten et al., 1997, Leviten and Posakony, 1996)
      Brdrv3
      Name Synonyms
      Secondary FlyBase IDs
        References (2)