FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\c(3)G1
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General Information
Symbol
Dmel\c(3)G1
Species
D. melanogaster
Name
FlyBase ID
FBal0001458
Feature type
allele
Associated gene
Dmel\c(3)G
Associated Insertion(s)
412{}c(3)G1
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Associated Insertion(s)
412{}c(3)G1
Cytology
Description

412 insertion into codon 115, resulting in an amino acid change Q115L followed by a stop codon.

(Page and Hawley, 2001)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Synaptonemal complexes absent from oocytes.

      (Lindsley and Zimm, 1992)

      Somatic pairing normal in homozygotes.

      (Semenov, 1979)

      Reported to be deficient for one of two X-ray-induced reactions leading to mitotic exchange.

      (Haendle, 1974)

      Increased sensitivity of c(3)G1-bearing sperm from c(3)G1/+ males to translocation induction.

      (Watson, 1972)

      Heterochromatic interchanges inducible in oocytes of homozygous females by X irradiation (see also FBrf0030974).

      (Roberts, 1969)

      Oocytes of homozygous females show increased sensitivity to X irradiation and lack the normally observed fractionation effect.

      (Watson, 1969)

      Both duration of meiotic prophase and number of 16-cell cysts per germarium reduced in homozygous females.

      (Smith and King, 1968)

      Intergenic recombination increased in heterozygous females (see also FBrf0023885).

      (Hinton, 1966)

      Meiotic loss of ring chromosomes increased in c(3)G1 females.

      (Sandler, 1965)

      Somatic crossing over normal in homozygotes.

      (LeClerc, 1946)

      Eliminates meiotic crossing over in homozygous females. First-division nondisjunction and chromosome loss frequent (30% for X, 2 and 3; 20% for 4); second division normal; exceptions more frequent at 25oC than at 19oC. Production of triploids and intersexes 300-500 times normal. Egg hatch very low. No meiotic effects in homozygous males. RK3.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Gowen.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      C(3)G17
      (Santos, 1999)
      C(3)G1
      (Huynh and St. Johnston, 2000)
      c(3)G17
      c(3)G1
      (Billmyre et al., 2019)
      cx
      Name Synonyms
      Secondary FlyBase IDs
        References (18)