FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ccbks127
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General Information
Symbol
Dmel\ccbks127
Species
D. melanogaster
Name
FlyBase ID
FBal0001561
Feature type
allele
Associated gene
Dmel\ccb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Martin-Peña and Ferrus, 2020)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

The coding region of ccb is intact - the lower expression of ccb in heads from ccbks127 flies indicates that the mutation could affect regulatory regions.

(Martin-Peña and Ferrus, 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ccbks127 homozygous adults exhibit morphological defects in ellipsoid body.

      (Martin-Peña and Ferrus, 2020)

      Mutants have impaired visual pattern memory.

      (Liu et al., 2006)

      Ellipsoid body and central body of central brain abnormally flat and broad; learning abnormal in tests using olfactory stimuli.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      ccbks127 has abnormal neuroanatomy | adult stage phenotype, enhanceable by spir[+]/spir1

      (Martin-Peña and Ferrus, 2020)
      Other
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ccbks127 has ellipsoid body phenotype, enhanceable by spir[+]/spir1

      (Martin-Peña and Ferrus, 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ccb1
      ccbKS127
      (Liu et al., 2006)
      ccbks127
      (Martin-Peña and Ferrus, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)