FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ctL1
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General Information
Symbol
Dmel\ctL1
Species
D. melanogaster
Name
FlyBase ID
FBal0002002
Feature type
allele
Associated gene
Dmel\ct
Associated Insertion(s)
gypsy{}ctL1
Carried in Construct
Also Known As
ctL-1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Lindsley and Zimm, 1992)
Progenitor genotype
Associated Insertion(s)
gypsy{}ctL1
Cytology
Description

gypsy insertion maps to the region between the block of embryonic ct enhancers and ct transcription start site.

(Dorsett, 1993)

DNA coordinates (FBrf0042060) (0 is gypsy site in ct6): +70.8 to +73.3

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Chie5.5; ctL1 double heterozygotes display a visible cut wing phenotype.

      (Morcillo et al., 1996)

      ct wing and vibrissae phenotype.

      (Dorsett, 1993)

      Homozygous embryos lack Malpighian tubules and the gut wall is 3--4 fold thicker than wild type at the junction of the posterior and anterior midgut.

      (Liu et al., 1991)

      Sense organ es to ch transformation. Malpighian tubules missing.

      (Blochlinger et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Shifting ctL1/ct2s; su(Hw)e2/su(Hw)2 embryos from 18oC to 29oC and vice versa demonstrates that the temperature sensitive period of su(Hw) gene product activity to block the ct wing enhancer is during pupariation, expression of ct is required just prior to pupariation and until 16-20h postpupariation.

      (Dorsett, 1993)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lim.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      lethal I cut phenotypic class.

      (Blochlinger et al., 1990)

      A cut lethal I phenotypic class allele.

      (Liu et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ctL-1
      (Morcillo et al., 1996, Dorsett, 1993, Liu et al., 1991)
      ctL1
      Name Synonyms
      Secondary FlyBase IDs
        References (8)