FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ddc2
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General Information
Symbol
Dmel\Ddc2
Species
D. melanogaster
Name
FlyBase ID
FBal0002251
Feature type
allele
Associated gene
Dmel\Ddc
Associated Insertion(s)
Carried in Construct
Also Known As
Ddcn2
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Wright et al., 1981)
Mutagen
ethyl methanesulfonate
(Wright et al., 1982, Wright et al., 1981, Wright et al., 1976)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ddcts1 heterozygotes with Ddc null alleles show temperature-dependent sterility.

      (Wright et al., 1981)

      Adult escapers of the lethality show prolonged development time and die within 24 hours of eclosion, their bristles are thin and straw coloured, and body does not darken, the wing axillae are melanized similar to the mutant phenotype of sp, the leg joints are melanized similar to a wound reaction, and they walk on their tibia rather than their tarsi, although they are coordinated.

      (Wright et al., 1976)

      Specific DDC activity of newly eclosed adult CyO/Ddc heterozygotes, as percentage of CyO/+ control: 53.3

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wright.

      Comments
      Comments

      Alleles of Ddc show intracistronic complementation. Ddc5 complements Ddc1, Ddc2, Ddc3, Ddc4, Ddc5, Ddc6 and Ddc8, and all complementary combinations involve Ddc5 or Ddc8.

      (Wright et al., 1976)

      Certain combinations of Ddc alleles show intragenic complementation.

      (Wright et al., 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ddc2
      Ddcn2
      (Wright et al., 1982, Wright et al., 1981, Wright et al., 1976)
      l(2)E57
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0042493
      References (4)