FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ddc7
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General Information
Symbol
Dmel\Ddc7
Species
D. melanogaster
Name
FlyBase ID
FBal0002256
Feature type
allele
Associated gene
Dmel\Ddc
Associated Insertion(s)
Carried in Construct
Also Known As
Ddcn7
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Heslip and Hodgetts, 1994, Wright et al., 1981)
Mutagen
ethyl methanesulfonate
(Wright et al., 1982, Wright et al., 1981, Wright et al., 1976)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ddcts2/Ddc7 adults raised at 18[o]C and then transferred to 25[o]C 4 days prior to infection show no difference in survival rates after infection with either E. coli or S. aureus compared to the survival rates of wild-type controls.

      (Davis et al., 2008)

      Larvae, unable to hatch from egg, are very active and have unpigmented (and perhaps incompletely sclerotinized) mouthparts and denticles.

      (Wright et al., 1982)

      Ddcts1 heterozygotes with Ddc null alleles show temperature-dependent sterility.

      (Wright et al., 1981)

      Ddc7/Df(2L)TW130 dies at the end of embryogenesis, unable to hatch fom the vitelline membrane, though muscle contractions are clearly evident. No morphological abnormalities are visible except that the cephalopharyngeal apparatus and setae remain unpigmented.

      (Wright et al., 1976)

      Specific DDC activity of newly eclosed adult CyO/Ddc heterozygotes, as percentage of CyO/+ control: 43.1

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer

      Wright.

      Comments
      Comments

      Certain combinations of Ddc alleles show intragenic complementation.

      (Wright et al., 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ddc7
      (Pan et al., 2022)
      Ddcn7
      (Davis et al., 2008, Bishop and Wright, 1987, Chen and Hodgetts, 1987, Wright et al., 1982, Wright et al., 1981, Wright et al., 1976)
      l(2)E140
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0029312
      References (9)