FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ddc43
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General Information
Symbol
Dmel\Ddc43
Species
D. melanogaster
Name
FlyBase ID
FBal0002292
Feature type
allele
Associated gene
Dmel\Ddc
Associated Insertion(s)
Carried in Construct
Also Known As
Ddcp1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wright et al., 1982)
Progenitor genotype
Cytology
Description

No lesion detectable on Southern blot.

(Wright et al., 1982)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal at 25oC over all non-conditional Ddc alleles tested (n=42) and all non-conditional, non-leaky l(2)37Ca alleles tested (n=27).

      (Wright et al., 1982)

      Specific DDC activity of newly eclosed adult CyO/Ddc heterozygotes, as percentage of CyO/+ control: 57.8 chromosome also lethal over l(2)37Ca

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Wright.

      Comments
      Comments

      Mutation is not a deficiency.

      (Wright et al., 1981)

      May be double mutant at the l(2)37Ca gene or alternatively be a polar mutation which alters or eliminates Ddc+ and l(2)37Ca+ functions. Certain combinations of Ddc alleles show intragenic complementation.

      (Wright et al., 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ddc43
      Ddcp1
      (Wright et al., 1982, Wright et al., 1981)
      l(2)620
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0042499
      References (5)