Homozygous females have ovaries which sometimes contain egg chambers with reversed polarity (16/225) or with mislocalised oocytes (14/225). 6-9% of embryos laid by homozygous females show perfect reversals in the left-right asymmetry of the proventriculus; its orientation is reversed, with its posterior part displaced to the left. The fraction of embryos derived from homozygous females showing this phenotype is not significantly altered by the paternal dic genotype. The reversal phenotype is extremely rare in embryos derived from dic¹/+ females, suggesting that it is a maternal rather than zygotic effect of the mutation.

Homozygous females produce egg chambers in which the oocyte is sometimes misplaced. Egg chambers in which the oocyte is positioned anteriorly develop normally although they have a reversed polarity with respect to the anterior-posterior axis of the whole ovariole. The follicle cell layer develops a reversed polarity; the terminal follicle cells at the anterior become posterior columnar follicle cells and the terminal follicle cells at the posterior acquire anterior fates.

Pole-cell transplantation experiments show that the dic¹ phenotype results if either the germ line or the soma or both are homozygous for dic¹.

One or several nurse cells may become detached from remainder of cyst.

A semidominant maternal-effect mutant with low penetrance. Homozygous dic¹ females and, to a lesser extent, dic¹/+ heterozygotes exhibit variable numbers of abnormal follicles and abnormal oocytes. During vitellogenesis, the oocyte occupies a position in the middle of or lateral to the nurse cells rather than posterior to them; the fifteen nurse cells distribute themselves into two clusters, one at each end of the follicle, instead of remaining together anteriorally, as normally occurs. The larger cluster tends to be located anteriorly. Chorionic respiratory processes irregular in shape and frequently point toward oviduct rather than germarium, as usually occurs. Eggs of dic¹ females form micropyle at both ends and they are less uniform in size and more irregular in shape than eggs from normal females. Embryonic development restricted to eggs of nearly normal shape. Blastoderm appears normal but no pole cells form. Head furrows and head lobes seen at both ends of embryo. Embryos secreting larval cuticle display (1) anterior denticle belt patterns at both ends, (2) a single abnormal polarity gradient, or (3) posterior pattern elements at both ends; segment showing polarity switch varies. The relative requencies of these three classes agree with hypothesis that the two ends of the egg develop independently with P (anterior development) = 0.9 for both ends.