FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\dppH88
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General Information
Symbol
Dmel\dppH88
Species
D. melanogaster
Name
FlyBase ID
FBal0003065
Feature type
allele
Associated gene
Dmel\dpp
Associated Insertion(s)
Carried in Construct
Also Known As
dppHin88
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Irish and Gelbart, 1987)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology

Polytene chromosomes normal.

(St. Johnston et al., 1990, Irish and Gelbart, 1987)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Fail to complete germ band extension, die with strong ventralized phenotype and no dorsal derived epidermis.

      (St. Johnston et al., 1990)

      Homozygotes have a ventralized embryonic phenotype: normally ventral epidermal pattern elements are present ventrally and dorsally. Clones of germ line tissue homozygous for dppH88, produced by inducing mitotic recombination in dppH88 Fs(2)M heterozygotes, demonstrate that the absence of maternal dpp product does not affect the zygotic phenotype.

      (Irish and Gelbart, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Allele class: Hin

      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dppH88
      dppHin88
      (St. Johnston et al., 1990, Irish and Gelbart, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)