FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Wedge1
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General Information
Symbol
Dmel\Wedge1
Species
D. melanogaster
Name
FlyBase ID
FBal0003111
Feature type
allele
Associated gene
Wedge
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Tearle et al., 1994)
Mutagen
spontaneous
(Tearle et al., 1994)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Severe disruption of eye development.

      (Tearle et al., 1994)

      homozygous lethal Eyes are small vertical wedges with points downward; much smaller than homozygous B. Lethal homozygous and in combination with Dr1, but Wedge1/DrMio survives (E.B. Lewis). RK1.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (1)
      Stocks (1)
      Notes on Origin
      Discoverer

      Muller.

      (Tearle et al., 1994)
      Comments
      Comments

      Wedge1/DrMio yields rare wild-type recombinants (Lewis).

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DrWe
      We
      Wedge1
      Name Synonyms
      Wedge
      Secondary FlyBase IDs
        References (2)