FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(spl)m8-HLHr26
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General Information
Symbol
Dmel\E(spl)m8-HLHr26
Species
D. melanogaster
Name
FlyBase ID
FBal0003347
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
Also Known As
l(gro)X115
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Preiss et al., 1988)
Progenitor genotype
E(spl)m8-HLH1
(de Celis et al., 1991)
Cytology

Polytene chromosomes normal.

(Preiss et al., 1988)
Description

Point mutation.

(Mari-Beffa et al., 1991)

Mutations in the m9/m10 coding region.

(de Celis et al., 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes that are also heterozygous for groBFP2 have eye defects that are similar but not identical to groBFP2 homozygotes. Homozygous mutant clones in the eye show ommatidial defects, often having extra photoreceptors.

      (Fischer-Vize et al., 1992)

      Homozygotes differentiate clusters of extra chaetae preferentially in the lateral regions of the tergites. This phenotype is exaggerated in heterozygotes with the revertant alleles E(spl)rv1 and Df(3R)E(spl)-rv27.

      (Mari-Beffa et al., 1991)

      Clusters of chaetae in the lateral region of the notum and extra microchaetae in the scutellum.

      (de Celis et al., 1991)

      Weak neurogenic phenotype.

      (Preiss et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      E(spl)gro
      (de Celis et al., 1991)
      E(spl)r26
      E(spl)m8-HLHr26
      gro
      (Mari-Beffa et al., 1991)
      groX115
      (Paroush et al., 1994)
      l(gro)X115
      (Fischer-Vize et al., 1992, Preiss et al., 1988)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)