FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\egl3
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General Information
Symbol
Dmel\egl3
Species
D. melanogaster
Name
FlyBase ID
FBal0003576
Feature type
allele
Associated gene
Dmel\egl
Associated Insertion(s)
Carried in Construct
Also Known As
eglPB23
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description

Splice site mutation between amino acids 126 and 127, the third intron is not excised.

(Mach and Lehmann, 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:23,738,625..23,738,625 [-]
Comment:

An unspecified mutation in the splice donor site. The splice site mutation has been arbitrarily mapped by a FlyBase curator to the first base of the splice donor site.

(Mach and Lehmann, 1997)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Double mutants with otu5 mutants display degenerate egg chambers, mutant phenotypes are cumulative.

      (Tirronen et al., 1993)

      Egg chambers contain 16 nurse cells and no oocyte, many egg chambers are degenerating.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      egl3
      (Mukherjee et al., 2006)
      eglPB23
      (Pare and Suter, 2000, Mach and Lehmann, 1997, Tirronen et al., 1993, Schupbach and Wieschaus, 1991)
      eglPB
      Name Synonyms
      Secondary FlyBase IDs
        References (5)