FB2026_02 , released June 18, 2026
Allele: Dmel\Eip74EF1
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General Information
Symbol
Dmel\Eip74EF1
Species
D. melanogaster
Name
FlyBase ID
FBal0003583
Feature type
allele
Associated gene
Dmel\Eip74EF
Associated Insertion(s)
Carried in Construct
Also Known As
E74X1001
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Caused by aberration
T(2;3)Eip74EF1
Cytology
Description

Breakpoint in the first intron of the E74A transcript of Eip74EF, 29kb upstream of the start sites of the E74B transcript.

(Karim and Thummel, 1991)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous pharate adults dissected from the pupal case display leg twitches and abdominal contractions and are inviable.

      (Fletcher et al., 1995)

      Homozygotes survive through the larval to prepupal transition but die by the pharate adult stage.

      (Karim and Thummel, 1991)

      pharate adult lethal

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Burtis, 1985.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E74X1001
      (Fletcher and Thummel, 1995, Fletcher et al., 1995)
      E74x1001
      Eip74EF1
      X1001
      (Karim and Thummel, 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)