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General Information
Symbol
Dmel\Flutter1
Species
D. melanogaster
Name
FlyBase ID
FBal0004116
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Normal electroretinogram.

Phenotype of heterozygotes is similar to that of Hk1 heterozygotes: ether-dependent leg shaking and wing scissoring. Flight ability is reduced and they show an impaired jump response. Homozygous flies are flightless and show greater agitation upon etherization. DLM, DVM and TDT muscles are swollen.

Flies heterozygous for Flu1, have reduced flight ability, impaired jump response and relatively slight disturbances in morphology of Z bands and myofibrils of indirect flight muscles; these Flu/+ flies are also like Hyperkinetic (Hk) mutants in terms of agitated behavior after etherization; Flu1/Flu1 flies are more severely affected with respect to flight and Hk-like phenotype; Flu1 studied for indirect flight muscle proteins and has reduced amounts of at least two high-molecular-weight materials.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

The chromosome carrying Flu1 may carry a second site mutation responsible for the hyperkinetic aspect of its phenotype.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Flu1
Flutter1
Name Synonyms
Secondary FlyBase IDs
    References (2)