FB2026_03 , released September 17, 2026
Allele: Dmel\fs(1)de10a
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General Information
Symbol
Dmel\fs(1)de10a
Species
D. melanogaster
Name
FlyBase ID
FBal0004263
Feature type
allele
Associated gene
fs(1)de10
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
PM hybrid dysgenesis
(Galanopoulos et al., 1989, Orr et al., 1989)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous females are sterile, and lay 14-18.8% as many eggs as wild-type. The endochorion is essentially normal, and the respiratory appendages are abnormal.

      (Galanopoulos et al., 1989)

      Mature follicles of homozygous females have no defects in the endochorion but have defective respiratory appendages.

      (Orr et al., 1989)

      morphologically abnormal eggs that fail to hatch. Various defects in respiratory appendages and chorionic architecture germ-line-dependent

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Germ line clonal analysis shows that fs(1)de10a is germ line-dependent.

      (Galanopoulos et al., 1989, Orr et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      de10
      (Orr et al., 1989)
      fs(1)de10
      (Galanopoulos et al., 1989)
      fs(1)de10a
      Name Synonyms
      Secondary FlyBase IDs
        References (2)