FlyBase Allele Report: Dmel\fs(1)ne8[a]

General Information

Symbol

Dmel\fs(1)ne8^a

Species

D. melanogaster

Name

FlyBase ID

FBal0004485

Feature type

allele

Associated gene

fs(1)ne8

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

PM hybrid dysgenesis

Nature of the Allele

Allele class

Mutagen

PM hybrid dysgenesis

(Galanopoulos et al., 1989, Orr et al., 1989)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | recessive

(Galanopoulos et al., 1989, Orr et al., 1989)

female sterile germline-dependent | recessive

Phenotype Manifest In

dorsal appendage

egg chorion

endochorion

(Galanopoulos et al., 1989, Orr et al., 1989)

oocyte

(Orr et al., 1989)

Detailed Description

Statement

Reference

Homozygous females are sterile, and lay fewer than 1% as many eggs as wild-type. The endochorion has moderate defects, and the respiratory appendages are essentially normal.

(Galanopoulos et al., 1989)

Homozygous females lay few or no eggs and show defects in oogenesis during choriogenesis. Follicles of homozygous females have major defects in the endochorion (which are uniformly distributed) but the respiratory appendages are normal.

(Orr et al., 1989)

Oviposition of few if any eggs. Various defects in respiratory appendages and chorionic architecture of hand dissected eggs.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Germ line clonal analysis shows that fs(1)ne8^a is germ line-dependent.

(Galanopoulos et al., 1989, Orr et al., 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

fs(1)ne8

(Galanopoulos et al., 1989)

fs(1)ne8¹

fs(1)ne8^a

ne8^a

(Orr et al., 1989)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close