FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fs(1)Ya6
Open Close
General Information
Symbol
Dmel\fs(1)Ya6
Species
D. melanogaster
Name
FlyBase ID
FBal0004494
Feature type
allele
Associated gene
Dmel\fs(1)Ya
Associated Insertion(s)
Carried in Construct
Also Known As
fs(1)Ya76, 13B-76
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Liu et al., 1995)
Mutagen
ethyl methanesulfonate
(Liu et al., 1995, Mohler, 1977)
Progenitor genotype
Cytology
Description

Amino acid replacement: S226F. Nucleotide substitution: C737T.

(Liu et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:2,725,077..2,725,077 [+]
Nucleotide change:

C2725077T

Reported nucleotide change:

C737T

Amino acid change:

S226F | fs(1)Ya-PA

Reported amino acid change:

S226F

(Liu et al., 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Females doubly mutant for gnu305 and fs(1)Ya6 or fs(1)Ya2 are indistinguishable from the fs(1)Ya embryos in terms of nuclear morphology.

      (Liu et al., 1997)

      Mutant embryos arrest either with multiple abnormal nuclei or at the pronuclear stage, with fewer than four abnormally condensed nuclei, presumably derived from the sperm and female meiotic products. 87% of embryos are pronuclear arrested, 13% have multiple abnormal nuclei.

      (Liu et al., 1995)

      Eggs are laid.

      (Mohler and Carroll, 1984)

      Homozygous females lay eggs that fail to hatch.

      (Mohler, 1977)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Mohler.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      13B-76
      (Mohler and Carroll, 1984, Mohler, 1977)
      fs(1)M1213B-76
      fs(1)Ya6
      fs(1)Ya76
      (Liu et al., 1997, Liu et al., 1995, Lin and Wolfner, 1991, Lin et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)