FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fu33
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General Information
Symbol
Dmel\fu33
Species
D. melanogaster
Name
FlyBase ID
FBal0004866
Feature type
allele
Associated gene
Dmel\fu
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
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        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Ovarioles of mutant females all contain tumorous egg chambers.

        (Vied and Horabin, 2001)

        temperature-sensitive allele fu wing-vein phenotype occurs at all temperatures; ocelli absent when raised at 22oC but not at 17oC. TSP for absence of anterior ocellus from second instar through pupal stage, for posterior ocelli restricted to late third instar and early pupal stage. Flightless when raised at 22oC or 29oC but not at 17oC; wings held horizontally perpendicular to body at 29oC. Musculature abnormal when raised at restrictive temperatures (Homyk and Grigliatti, 1983).

        External Data
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        Phenotypic Class
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        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (2)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Distribution of Sxl product in ovaries is abnormal, the transtition from cytoplasmic to nuclear distribution does not occur. Most if not all of the small germ cells that populate the tumorous cysts show high levels of Sxl protein. Sxl splicing occurs exclusively in the female mode. Temperature shift experiments indicate that only the early steps in oogenic differentiation are affected.

        (Bopp et al., 1993)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        fu33
        futs1
        who
        Name Synonyms
        Secondary FlyBase IDs
          References (3)