FB2026_02 , released June 18, 2026
Allele: Dmel\Got1lo
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General Information
Symbol
Dmel\Got1lo
Species
D. melanogaster
Name
FlyBase ID
FBal0005125
Feature type
allele
Associated gene
Dmel\Got1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Chase and Kankel, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant has low Got1 activity.

      (Chase and Kankel, 1987)

      low activity; Got1lo homozygotes normal in viability and fertility.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Got1lo Got2unspecified double homozygotes have reduced viability, especially under crowded conditions. Those animals that do not survive die as externally normal pharate adults, and those that do survive eclose later than their control siblings. The surviving double homozygotes do not show normal pattern preference behaviour, some cannot fly, and they do not appear to be phototactic. Their electroretinograms are normal.

      (Chase and Kankel, 1987)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Got1lo
      Name Synonyms
      Secondary FlyBase IDs
        References (1)