FB2026_02 , released June 18, 2026
Allele: Dmel\Gtd1
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General Information
Symbol
Dmel\Gtd1
Species
D. melanogaster
Name
FlyBase ID
FBal0005260
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
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Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
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Disease
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Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
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Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adults show a reduced response to sucrose in a feeding preference test. This phenotype is semidominant. Adults show an enhanced attraction to 100mM sodium chloride compared to wild-type, and tolerance to 0.5M NaCl and 0.2M potassium chloride. This phenotype is partially dominant. The threshold of avoidance of quinine is increased compared to wild-type. This phenotype is partially dominant. Homozygous adults show a normal electrophysiological response from the labellar chemoreceptors in response to 100mM NaCl or sucrose. Gtd1/Dp(1;Y)y+v+#3 flies die as second instar larvae.

Enhanced attraction to NaCl in feeding-preference test, NaCl tolerance in ingestion test, relative indifference to sucrose and higher than normal threshold for quinine avoidance; all of these phenotypes semidominant. Gustatory responses of larvae normal. No alteration in electrophysiologically measured response of peripheral (labellar) neurons to NaCl; causes lethality of males hemizygous for the mutation who also carry duplication for normal allele. When heterozygous with gustC, which is closely linked, flies show reduced response to sucrose that is more severe than in tests of either homozygous or hemizygous type; three revertants of Gtd/y+Yv+#3 lethal interaction also reverted with respect to sucrose-indifference phenotype.

External Data
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Additional Comments
Genetic Interactions
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Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Fails to complement nearby gustD mutations with respect to (recessive-type) quinine tolerance. complements gustB in behavioral assays (re homozygous-type responses).

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Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: Feeding-preference enrichment, against positive glucose response.

Comments
Comments

Isolated after selective enrichment of the progeny of mutagenised flies for insensitivity to 10mM glucose in a feeding preference test.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
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Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)