FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gustBx5
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General Information
Symbol
Dmel\gustBx5
Species
D. melanogaster
Name
FlyBase ID
FBal0005272
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
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Allele class
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Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
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Location
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Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
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Marker for
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Reporter construct used in assay
Human Disease Associations
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Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adults respond normally to sucrose in a feeding preference test. Adults show an enhanced attraction to 100mM sodium chloride (NaCl) compared to wild-type, and are tolerant to 0.5M NaCl. This phenotype is fully recessive. Homozygous adults show an elevated spike frequency from the labellar chemoreceptors in response to 100mM NaCl. The electrophysiological response to sucrose is normal.

Homozygous adults show a markedly greater preference for sodium chloride (NaCl) in feeding preference and proboscis extension tests compared to wild-type flies. The proboscis extension response evoked by 10mM sucrose shows an increased tolerance to NaCl. The chemosensory neurons of homozygous labellar taste hairs show an enhanced electrophysiological response when stimulated by NaCl compared to wild-type flies. The S neuron is stimulated by NaCl in homozygotes, in contrast to wild-type. The S neuron is also stimulated by sucrose in homozygotes, as in wild-type flies. Taste sensilla of all types are affected, but the effect is most clearly seen in the P-type hairs. The branching pattern and the dendritic morphology of the neurons of the labellar taste hairs appear normal.

Taste mutant that affects the fly's responses to attractants and repellents. Originally said to be "indifferent" to sodium chloride (NaCl), but now known to give positive responses (greater than wild type) to this salt in the feeding preference test which consist of behavioral (proboscis extension) and physiological (labellar recording) responses (Arora). Responds normally to sucrose (C12H22O11) and quinine (C20H24N2O2).

External Data
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Mutant
Wild-type
Stocks (1)
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External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
gustBx5
Name Synonyms
Secondary FlyBase IDs
    References (2)