FB2026_02 , released June 18, 2026
Allele: Dmel\Hsp60AF409
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General Information
Symbol
Dmel\Hsp60AF409
Species
D. melanogaster
Name
FlyBase ID
FBal0005911
Feature type
allele
Associated gene
Dmel\Hsp60A
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

Nucleotide substitution: C to T. Amino acid replacement: S154L.

(Perezgasga et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:11,110,504..11,110,504 [+]
Nucleotide change:

C11110504T

Reported nucleotide change:

C?T

Amino acid change:

S155L | Hsp60A-PA; S155L | Hsp60A-PB

Reported amino acid change:

S154L

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Perezgasga et al., 1999)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die very early during embryogenesis with no signs of gastrulation.

      (Perezgasga et al., 1999)

      Embryos have an amorphous shape just before gastrulation.

      (Kozlova et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Hsp60AF409 is rescued by Hsp60A+t15

      (Kozlova et al., 1997)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      Hsp60F409
      Hsp60AF409
      hsp60F409
      (Perezgasga et al., 1999)
      l(1)10Ac11
      l(1)10AcF409
      (Kozlova et al., 1997)
      l(1)BP5F409
      (Zhimulev et al., 1987)
      l(1)F409
      Name Synonyms
      Secondary FlyBase IDs
        References (3)