FB2026_02 , released June 18, 2026
Allele: Dmel\l(1)adl161
Open Close
General Information
Symbol
Dmel\l(1)adl161
Species
D. melanogaster
Name
FlyBase ID
FBal0007397
Feature type
allele
Associated gene
l(1)adl16
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Homyk et al., 1986)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult flies have an extended proboscis and a swollen abdomen (temperature-sensitive phenotype). Adults show temperature-sensitive lethality; they die 5-8 days after eclosion at 29oC. There is also a temperature-sensitive semi-lethal period during preimaginal development, during the embryonic to second larval instar stage.

      (Homyk et al., 1986)

      temperature-sensitive embryonic/larval lethal temperature-sensitive swollen abdomen; proboscis extended; flight reduced adults die 2-20 days after eclosion at 29oC. temperature-sensitive swollen abdomen; proboscis extended time of death: 5-8

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Cross.

      Comments
      Comments

      The temperature-sensitive proboscis and abdomen phenotype has not been genetically localised, and could therefore be due to a second-site mutation.

      (Homyk et al., 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      DC836
      l(1)adl-16ts1
      (Homyk et al., 1986)
      l(1)adl161
      Name Synonyms
      Secondary FlyBase IDs
        References (3)