FB2026_02 , released June 18, 2026
Allele: Dmel\l(1)adl21
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General Information
Symbol
Dmel\l(1)adl21
Species
D. melanogaster
Name
FlyBase ID
FBal0007400
Feature type
allele
Associated gene
l(1)adl2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Homyk et al., 1986)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult flies are hypoactive. Adults die 3-7 days after eclosion at 29oC. Mosaic analysis reveals paired lethal foci that appear to map in the vicinity of the subesophageal ganglion.

      (Homyk et al., 1986)

      Fate mapping suggests presence of bilateral domineering foci located in or near the subesophageal ganglion responsible for both hypoactivity and lethality at 29oC (Homyk, Sinclair, Wong and Grigliatti, 1986). not temperature-sensitive during development hypoactive adults die 3-7 days after eclosion at 29oC.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(1)adl-2ts1
      (Homyk et al., 1986)
      l(1)adl21
      Name Synonyms
      Secondary FlyBase IDs
        References (1)