FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gli1
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General Information
Symbol
Dmel\Gli1
Species
D. melanogaster
Name
FlyBase ID
FBal0008532
Feature type
allele
Associated gene
Dmel\Gli
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12, Auld et al., 1995, Roote, 1995.5.4)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      embryonic salivary gland & epithelial cell

      (Genova and Fehon, 2003)

      septate junction

      (Genova and Fehon, 2003)
      Detailed Description
      Statement
      Reference

      Gli1 mutants exhibit disruption of the paracellular barrier in the embryonic salivary gland. In Gli1 homozygous mutants the adherens junction remains intact, with the regular spacing of plasma membranes maintained. However, the septae normally located between these membranes are reduced in number or absent.

      (Genova and Fehon, 2003)

      Gli1 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces viable flies.

      (Sawamura et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      El Messal.

      P. Simpson.

      (Roote, 1995.5.4)
      Comments
      Comments

      Phenotypic data included in FBrf0051973.

      (Roote, 1995.5.4)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Gli1
      (Christensen et al., 2008.12.28)
      GliP29
      (Sawamura et al., 2000)
      P29
      (Roote, 1995.5.4)
      l(2)35DgP29
      (Auld et al., 1995)
      l(2)br45P29
      (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)