FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Catsup12
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General Information
Symbol
Dmel\Catsup12
Species
D. melanogaster
Name
FlyBase ID
FBal0008630
Feature type
allele
Associated gene
Dmel\Catsup
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Wright, 1996, Stathakis et al., 1995)
Mutagen
ethyl methanesulfonate
formaldehyde
Progenitor genotype
Cytology
Description

Contains an aberration that eliminates an internal PstI site.

(Stathakis et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous adults are hyperactive (showing increased overall activity) and show increased grooming behaviour compared to wild type.

      (Wang et al., 2011)

      65-75% of the hemizygous or homozygous lethality of Catsup12 occurs between the late embryonic period and the second larval instar, while approximately 12-17% of the lethality occurs during the third larval instar stage. Lethality also occurs during pupariation. Catecholamine pool levels are abnormal in homozygous embryos.

      (Stathakis et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wright.

      Comments
      Comments

      Group IV lethal.

      (Stathakis et al., 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Bc12
      (Wright, 1996)
      Catsup12
      (Wang et al., 2011)
      l(2)37Bc12
      (Stathakis et al., 1995)
      l(2)380
      Name Synonyms
      Secondary FlyBase IDs
        References (6)