FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cub1
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General Information
Symbol
Dmel\cub1
Species
D. melanogaster
Name
FlyBase ID
FBal0008662
Feature type
allele
Associated gene
cub
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
gamma ray
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous pupae are larger and darker than wild-type, and many contain an abnormal air space in the posterior end. The pupae usually contain one large melanotic tumour, and show a complete lack of cuticle differentiation, except possibly over the genital region. The eye-antennal discs evert but the leg and wing discs do not.

      (Wright, 1996)

      Hemizygous cub1/Df(2L)TW130 animals survive to the late third larval instar stage. cub1/Df(2L)TW130 ovaries from third instar larvae transplanted into wild-type late third instar host larvae are not detectable in the adult host flies.

      (McCrady and Tolin, 1994)

      Pupae with large melanotic tumors.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Wright.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Bg1
      (Wright, 1996)
      cub1
      l(2)37Bg1
      (McCrady and Tolin, 1994)
      l(2)7420
      Name Synonyms
      Secondary FlyBase IDs
        References (3)