FB2026_02 , released June 18, 2026
Allele: Dmel\magoWE7
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General Information
Symbol
Dmel\magoWE7
Species
D. melanogaster
Name
FlyBase ID
FBal0009127
Feature type
allele
Associated gene
Dmel\mago
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description

Amino acid replacement: I91T.

(Newmark and Boswell, 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:21,129,023..21,129,023 [+]
Nucleotide change:

T21129023C

Amino acid change:

I91T | mago-PA

(Newmark and Boswell, 1994)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      magoWE7 has lethal phenotype, suppressible by Cele\mag-1mago.PN

      (Newmark et al., 1997)
      Other
      Statement
      Reference

      Cele\mag-1mago.PN, magoWE7 has viable phenotype

      (Newmark et al., 1997)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      A single copy of Cele\mag-1mago.PN is sufficient to rescue the zygotic lethality caused by magoWE7.

      (Newmark et al., 1997)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Mackay.

      Comments
      Comments

      Shows interallelic complementation for zygotic lethality with mago1 and magoE19A.

      (Newmark and Boswell, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      WE7
      (Newmark et al., 1997)
      l(2)57Ca5
      l(2)WE7
      magoWE7
      Name Synonyms
      Secondary FlyBase IDs
        References (3)