Heterozygous InR^93Dj-1 mutant flies reared on food containing 7.5% ethanol exhibit reduced adult viability compared to controls. Viability is comparable with controls when flies are raised on conventional media.

In a fed state, InR^93Dj-1 flies are anoxia tolerant.

InR^93Dj-1/InR^E19 adults are dwarf in size and are short-lived; life expectancy of both males and females is reduced compared to controls (from 32.3 to 2.3 and from 35.5 to 1.4 days respectively).

Heterozygous adults have slightly reduced body size. Many InR^93Dj-1/InR^E19 animals survive to adulthood. They eclose with a delay of 8 to 9 days at 25^oC, having prolonged second and third larval instar stages compared to control siblings. The number of cells in the wing, eye-antennal, haltere, mesothoracic leg and metathoracic leg discs is reduced compared to wild-type. Pupae and adult flies are reduced in size compared to wild-type. InR^93Dj-1/InR^E19 males are fertile, but InR^93Dj-1/InR^E19 females are unable to produce eggs. Ovaries are reduced in size, do not contain mature eggs and remain unchanged in size at 7, 10 and 14 days after eclosion. The rate of ovariole maturation is slower than wild-type and ovarioles never mature to the stage of egg deposition.