FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lcp2F
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General Information
Symbol
Dmel\Lcp2F
Species
D. melanogaster
Name
FlyBase ID
FBal0011585
Feature type
allele
Associated gene
Dmel\Lcp2
Associated Insertion(s)
Carried in Construct
Also Known As
2/3
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Snyder et al., 1982)
Progenitor genotype
Cytology
Description

Amino acid replacement: S18L.

(Snyder et al., 1982)

A to C change is in the 3' untranslated region. Lcp2F differs from the Canton S Lcp2S allele by three single base changes.

(Snyder et al., 1982)

Amino acid replacement: R108S.

(Snyder et al., 1982)

Nucleotide substitution: C?T.

(Snyder et al., 1982)

Nucleotide substitution: C?A.

(Snyder et al., 1982)

Nucleotide substitution: A?C.

(Snyder et al., 1982)

Lcp2F gene product has been shown to differ from that of the more common Lcp2S allele by two amino acid substitutions

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
sequence_variant
2R:8,434,371..8,434,371 [-]
Nucleotide change:

C3103T

Amino acid change:

S34L | Lcp2-PA; S34L | Lcp2-PB

Comment:

First of three differences between Lcp2S and Lcp2F alleles; amino acid change reported for longest CDS; amino acid difference reported as S18L in FBrf0038659 indicates position on the mature peptide.

(Snyder et al., 1982)
sequence_variant
2R:8,434,102..8,434,102 [-]
Nucleotide change:

C3372A

Amino acid change:

R124S | Lcp2-PA; R124S | Lcp2-PB

Comment:

Second of three differences between Lcp2S and Lcp2F alleles; amino acid change reported for longest CDS; amino acid difference reported as R108S in FBrf0038659 and indicates position on the mature peptide.

(Snyder et al., 1982)
sequence_variant
2R:8,434,063..8,434,063 [-]
Comment:

Third of three differences between Lcp2S and Lcp2F alleles; nucleotide is C in Lcp2F alleles and in reference sequence, and A in Lcp2S.

(Snyder et al., 1982)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced with: Lcp3n1.

      Comments
      Comments

      Recovered from a natural population in Australia in 1977. Associated with Lcp3n1.

      (Snyder et al., 1982)

      The chromatin structure of the larval cuticle gene cluster at 44D (Lcp1, Lcp1Ψ, Lcp2, Lcp3 and Lcp4) has been characterised in Lcp3n1 embryos.

      (Eissenberg et al., 1984)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      2/3
      (Eissenberg et al., 1984, Chihara et al., 1982)
      CPf2
      (Snyder et al., 1982)
      Lcp-f2
      (Kimbrell et al., 1989)
      Lcp2F
      Name Synonyms
      Secondary FlyBase IDs
        References (5)