FB2026_02 , released June 18, 2026
Allele: Dmel\mei-2511
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General Information
Symbol
Dmel\mei-2511
Species
D. melanogaster
Name
FlyBase ID
FBal0012146
Feature type
allele
Associated gene
mei-251
Associated Insertion(s)
Carried in Construct
Also Known As
mei-251
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
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        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Reduces meiotic exchange.

        (Carpenter and Baker, 1982)

        Hemizygous male larvae are not sensitive to HN2 and MMS.

        (Mason et al., 1981)

        Mutants are weakly recombination defective. Mutants do not show sensitivity to UV light, γ rays or X rays. Homozygotes and hemizygotes do not show an increased frequency of spontaneous chromosome aberrations in neuroblast metaphases compared to wild-type larvae.

        (Gatti, 1979)

        Females homozygous for mei-2511 exhibit reduced levels of meiotic exchange (to approximately 80% of control levels). The residual exchanges are distributed such that the probability of euchromatic exchange becomes more nearly proportional to polytene-chromosome length (FBrf0023919, Carpenter and Sandler, 1974, FBrf0028329). Both X and fourth chromosomal nondisjunction are slightly elevated, presumably as a consequence of decreased recombination.

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
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        Additional Comments
        Genetic Interactions
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        Xenogenetic Interactions
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        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        mei-251
        (Carpenter and Baker, 1982, Mason et al., 1981, Gatti, 1979)
        mei-2511
        Name Synonyms
        Secondary FlyBase IDs
          References (3)