FB2026_03 , released September 17, 2026
Allele: Dmel\ms(1)71
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General Information
Symbol
Dmel\ms(1)71
Species
D. melanogaster
Name
FlyBase ID
FBal0012486
Feature type
allele
Associated gene
ms(1)7
Associated Insertion(s)
Carried in Construct
Also Known As
ms(1)7
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Geer et al., 1979, Geer and Bowman, 1977)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Spermiogenesis is normal in every way in mutant males. Sperm head maturation is normal. The sperm of ms(1)71/Y males enter the egg but do not complete fertilisation.

      (Dybas et al., 1981)

      Mutant males have many motile sperm in the testes. The viability of ms(1)71/+ females and ms(1)71/Y males is the same. Post-copulatory sperm from ms(1)71/Y males observed in the seminal receptacles of wild-type females show no ultrastructural differences to wild-type controls and the number of sperm transmitted to females during copulation is similar to wild type. Females housed continuously with males lay the same number of eggs regardless of whether they have been mated with ms(1)71/Y or wild-type males. Females mated to ms(1)71/Y males and then isolated lay only 25% as many eggs as females kept with ms(1)71/Y males. This reduction is greater than that seen when females are mated with wild-type males and then isolated (54% reduction). Sperm from ms(1)71/Y males are able to enter the egg.

      (Geer et al., 1979)

      Mutation blocks a late sperm function during the fertilisation process.

      (Geer and Bowman, 1977)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ms(1)7
      (Dybas et al., 1981, Geer et al., 1979)
      ms(1)71
      Name Synonyms
      Secondary FlyBase IDs
        References (3)