FB2026_03 , released September 17, 2026
Allele: Dmel\mu11
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General Information
Symbol
Dmel\mu11
Species
D. melanogaster
Name
FlyBase ID
FBal0012568
Feature type
allele
Associated gene
mu1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The incidence of y1 and f36a clones is five times control values in mu11/mu11 and ten times control in mu11/Df(3R)sbd105 females.

      (Martensen and Green, 1976)

      The effects of 100r on the induction of sex-linked lethals is significant in mu11 but not + females.

      (Gold and Green, 1975)

      Homozygous and hemizygous females exhibit increased rates of sex-linked visible and lethal mutations (e.g., y2 --> y+ = 1/2500; more rarely mutations to intermediate or more extreme alleles; also f3N reversions and wa --> w); heterozygous females display slightly elevated rates of mutation; about half of mutants occur as clusters indicating a premeiotic origin. Lethal mutations frequently associated with deficiencies of one to several bands. Mutation rates not elevated in males. y - sn recombination reduced 30% in mu11 homozygous and 25% in mu11/+ heterozygous females; also females but not males display elevated frequencies of nondisjunction.

      External Data
      Interactions
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      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
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      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The frequency of X ray induced dominant lethals and sex-linked recessive lethals in stage 7 oocytes is similar in mu11 and wild-type females. The frequency of X ray induced X chromosome loss in stage 7 oocytes is higher in mu11 females than wild-type females, although this difference is only statistically significant at higher doses of 3000 and 3750R and not at lower doses of 750-2250R. The frequency of X ray induced sex-linked recessive lethals in pre-meiotic germ cells is similar in mu11 and wild-type females.

      (Sankaranarayanan, 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mu11
      μ
      (Sankaranarayanan, 1982)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)