FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mus101ts1
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General Information
Symbol
Dmel\mus101ts1
Species
D. melanogaster
Name
FlyBase ID
FBal0012592
Feature type
allele
Associated gene
Dmel\mus101
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Smith et al., 1985)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Strong defect in chromosome condensation restricted to the heterochromatic regions.

      (Verni et al., 1995)

      mus101ts1/mus101D2 females are hypersensitive to killing by MMS and have reduced fertility. Homozygous females have reduced fertility. Chromosome condensation is abnormal in homozygous third instar larval ganglia at 29oC, but normal at 18oC. Only heterochromatic portions of the genome are affected, being undercondensed, at 29oC. Approximately 2% of cells contain broken chromosomes.

      (Smith et al., 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      mus101ts1 is rescued by mus101+t9

      (Yamamoto et al., 2000)
      Not rescued by

      mus101ts1 is not rescued by mus101tB10

      (Yamamoto et al., 2000)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Baker.

      Selected as: temperature-sensitive lethal that shows an elevated frequency of homozygous mwh clones in the wing of mit(1)141/Y;mwh-/+ males.

      (Smith et al., 1985)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mus-101ts
      (Smith et al., 1985)
      mus101ts1
      mus101tsl
      (Yamamoto et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)