FB2026_02 , released June 18, 2026
Allele: Dmel\mus310D1
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General Information
Symbol
Dmel\mus310D1
Species
D. melanogaster
Name
FlyBase ID
FBal0012664
Feature type
allele
Associated gene
mus310
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Boyd et al., 1981)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies are sensitive to X rays.

      (Oliveri et al., 1990)

      Displays hypermutability to alkylating agents; defective both in alkylation and UV excision repair pathways.

      (Smith and Dusenbery, 1988)

      Cells derived from homozygous embryos have a reduced ability to synthesise DNA after UV irradiation compared to wild-type cells. Homozygous larval brain ganglia have a reduced ability to synthesise DNA both from an undamaged template and after exposure to N-acetoxy-2-acetylaminofluorene compared to wild-type.

      (Boyd and Shaw, 1982)

      Sensitive to 0.025% methyl methanesulfonate. Not sensitive to 0.008% HN2.

      (Boyd et al., 1981)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Homozygotes have normal excision repair capabilities, but postreplication repair is reduced compared to wild-type. Homozygous cultured cells respond to UV irradiation with unusually low thymidine incorporation and with the synthesis of abnormally short nascent DNA.

      (Brown and Boyd, 1981)

      mus310D1 has no detectable effect on the recovery of chromosomes undergoing P-element transposition.

      (Banga et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mus310D1
      Name Synonyms
      Secondary FlyBase IDs
        References (9)