FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\NM
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General Information
Symbol
Dmel\NM
Species
D. melanogaster
Name
of Mischaikow
FlyBase ID
FBal0012780
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
FB{}NM
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Cicak and Oster, 1957)
Progenitor genotype
Associated Insertion(s)
FB{}NM
Cytology
Description

The Notch locus in the reverted chromosome N+M contains an insertion homologous to the FB4 foldback element (Grimwade, Muskavitch, Welshons, Yedvobnick and Artavanis-Tsakonas).

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal in hemizygous males. Females show notching of the tips and occasionally of the edges of the wing, have thickened veins which broaden to form deltas, slightly smaller eyes than normal and infrequently a gross reduction of one eye. NM/Nspl-1 flies have roughened eyes which are smaller than normal and split bristles.

      (Cicak and Oster, 1957)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Mischaikow, Dec. 1956.

      Mischaikow, Dec. 1956

      (Cicak and Oster, 1957)

      Arose on: In(1)dl-49, y w f component of C(1)DX.

      Induced on: In(1)dl-49, y w f of a "doubly-attached" X chromosome.

      (Cicak and Oster, 1957)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      NM
      Name Synonyms
      of Mischaikow
      Secondary FlyBase IDs
        References (2)