Comments on Models/Modifiers Based on Experimental Evidence
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Phenotype Manifest In
Homozygous ndl2 follicle cell clones are produced via Scer\GAL4e22c-mediated expression of FLP recombinase. In some egg chambers all follicle cells appear to be mutant, indcating that ndl2 mutants do not confer any defect in viability or growth.
Ventral follicle cells homozygous for the class II ndl2 allele do not perturb dorso-ventral patterning in the progeny embryos.
Embryos transplanted with perivitelline fluid from Tl2 embryos exhibit a polar gastrulation. At the end of embryogenesis an almost complete restoration of pattern along the dorsoventral axis is seen. The point of injection determines the ventralmost point of the restored pattern.